• 马斌

    长聘教轨副教授,博士生导师。2005年获兰州大学生物科学专业学士学位。 2007年获得荷兰格罗宁根大学医学制药学专业优等硕士学位(cum laude)。2012年获荷兰特文特大学博士学位,并获得2011年度国家优秀自费留学生奖学金。2013年至2015年在瑞士苏黎世大学及附属儿童医院从事博士后研究工作。2015年10月加入amjs澳金沙门线路。2016年获得上海高校青年东方学者称号。

教育背景

2007/10至2012/09, 荷兰特文特大学, 细胞与分子生物学, 博士

2005/09至2007/07, 荷兰格罗宁根大学, 医学制药学, 硕士

2001/09至2005/06, 兰州大学, 生物科学, 学士

工作经历

2015/10至现在, amjs澳金沙门线路, amjs澳金沙门线路, 副研究员

2014/02至2015/06, 瑞士苏黎世大学附属儿童医院, 博士后

2013/01至2014/08, 瑞士苏黎世大学, 博士后

研究方向
致癌通路和肿瘤微环境,肿瘤内源性免疫逃逸机制,癌症的免疫疗法。
代表性论文专著
  • Gui L#, Wang Z#, Lou W#, Yekehfallah V, Basiri M, Gao WQ, Wang Y*, Ma B*. Comparative evaluation of antitumor effects of TNF superfamily costimulatory ligands delivered by mesenchymal stem cells. Int Immunopharmacol 2024; 126: 111249. #Co-first author; *Corresponding author
  • Yekehfallah V, Pahlavanneshan S, Sayadmanesh A, Momtahan Z, Ma B*, Basiri M*. Generation and functional characterization of PLAP CAR-T cells against cervical cancer cells. Biomolecules 2022; 12: 1296. *Corresponding author
  • Ji L, Peng P, Gui L, Yuan P, Qian W, Wang Y, Gao WQ*Ma B*.  CD24 is a superior immunotherapeutic target to PD-1 in a mouse model of Helicobacter-induced gastric cancer. Gastro Hep Advances 2022; 1(1):79-82. *Corresponding author
  • Yan J, Yuan P, Gui L, Wang Z, Yin P, Gao WQ, Ma B*. CCL28 downregulation attenuates pancreatic cancer progression through tumor cell-intrinsic and -extrinsic mechanisms. Technol Cancer Res Treat 2021; 20:15330338211068958. *Corresponding author
  • Wang C#, Yan J#, Yin P, Gui L, Ji L, Ma B*, Gao WQ*. β-Catenin inhibition shapes tumor immunity and synergizes with immunotherapy in colorectal cancer. OncoImmunology 2020; 9(1): e1809947. #Co-first author; *Corresponding author
  • Yin P, Gui L, Wang C, Yan J, Liu M, Ji L, Wang Y, Ma B*, Gao WQ*. Targeted delivery of CXCL9 and OX40L by mesenchymal stem cells elicits potent antitumor immunity. Mol Ther 2020; 28(12):2553-63.  *Corresponding author 
  • Ji L, Qian W, Gui L, Ji Z, Yin P, Lin GN, Wang Y, Ma B*, Gao WQ*. Blockade of β-catenin-induced CCL28 suppresses gastric cancer progression via inhibition of Treg cell infiltration. Cancer Res 2020; 80(10):2004-16. *Corresponding author
  • Ma B, Hottiger MO. Crosstalk between Wnt/β-catenin and NF-κB signaling during inflammation. Front Immunol 2016; 7:378.
  • Ma B, Fey M, Hottiger MO. WNT/β-catenin signaling inhibits CBP-mediated RelA acetylation and expression of a proinflammatory subset of NF-κB target genes. J Cell Sci 2015; 128:2430-2436.
  • Ma B, Zhong L, van Blitterswijk CA, Post JN, Karperien M. T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor κB signaling. J Biol Chem 2013; 288:17552-8.
  • Ma B, van Blitterswijk CA, Karperien M. A Wnt/β-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes. Arthritis Rheum 2012; 64:2589-600.
  • Ter Elst A#, Ma B#Scherpen FJG, de Jonge HJ, Douwes J, Wierenga AT, Schuringa JJ, Kamps WA, de Bont ES. Repression of vascular endothelial growth factor expression by the runt-related transcription factor 1 in acute myeloid leukemia. Cancer Res 2011; 71:2761-71. #Co-first author
教学工作

免疫疾病与肿瘤免疫基础 (32学时,研究生)

免疫与健康 (32学时,本科生)

联系方式

邮箱地址:binma@sjtu.edu.cn

办公地址:徐汇校区教三楼503室